Researchers at McMaster University in Canada found that the meds can prevent major organs from functioning properly by blocking the absorption of serotonin – a vital chemical that is used by the heart, kidneys, lungs and liver from the body’s bloodstream.
“We are very concerned by these results,” said author Paul Andrews, an associate professor at McMaster who led the research team. “They suggest that we shouldn’t be taking antidepressant drugs without understanding precisely how they interact with the body.”
Scientists pooled data from hundreds of thousands of people to get the results.
They also found that those who down antidepressants had a 14 percent higher risk for cardiovascular problems, like stroke and heart attack.
The results were published Thursday in the journal Psychotherapy and Psychosomatics.
One in eight adults Americans take antidepressants, which are among the most commonly used medications.
The McMaster study undermines the idea that antidepressants actually save lives by reducing depressive symptoms, according to co-author Marta Maslej.
“Our findings are important because they undermine this assumption. I think people would be much less willing to take these drugs if they were aware how little is known about their impact outside of the brain, and that what we do know points to an increased risk of death.”
The study also found antidepressants aren’t harmful to people with cardiovascular diseases, like heart disease and diabetes, which could be because the medication can have blood-thinning effects.